Comparison of The Effect of 5-MTHF and Folic Acid Supplementation in Increasing Red Blood Cell Folate in Pregnant Women

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

August 31, 2025

Study Completion Date

January 1, 2026

Conditions
Pregnant Women
Interventions
DIETARY_SUPPLEMENT

Folic Acid

Participants in this group will receive a daily oral dose of 600 mcg (1.35 μmol) of folic acid in film-coated tablet form for a duration of three months. This synthetic form of folate will be administered to assess its impact on red blood cell folate levels compared to 5-MTHF.

DIETARY_SUPPLEMENT

5-MTHF (5-methyltetrahydrofolate)

Participants in this group will receive a daily oral dose of 1100 mcg (1.35 μmol) of 5-methyltetrahydrofolate (5-MTHF) glucosamine salt, specifically HY-FOLIC®, in film-coated tablet form for a duration of three months. This active form of folate will be administered to assess its impact on red blood cell folate levels compared to folic acid

Trial Locations (1)

60114

RECRUITING

Mulyorejo Public Health, Surabaya

Sponsors
All Listed Sponsors
collaborator

Prodia Diacro Laboratories P.T.

INDUSTRY

collaborator

Simex Pharmaceutical Indonesia

UNKNOWN

lead

Dr. Soetomo General Hospital

OTHER_GOV