C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 31, 2026

Primary Completion Date

November 30, 2028

Study Completion Date

December 31, 2029

Conditions
Lupus Nephritis (LN)
Interventions
BIOLOGICAL

C-CAR168

This is a multi-center, Phase 1/2, open-label, dose-escalation and dose-expansion study evaluating C-CAR168 for the treatment of autoimmune diseases refractory to standard therapy. A traditional 3+3 design is used to identify the Maximum Tolerated Dose (MTD) and/or Recommended Dose (RD) in disease-specific cohorts.

Trial Locations (1)

20850

AbelZeta, Inc., Rockville

All Listed Sponsors
lead

AbelZeta Inc.

INDUSTRY

NCT06935474 - C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease | Biotech Hunter | Biotech Hunter