150
Participants
Start Date
November 1, 2025
Primary Completion Date
November 1, 2030
Study Completion Date
November 1, 2033
Semaglutide 2.4 mg
The dosing regimen will follow standard titration protocols, starting with a dose of 0.25 mg weekly for the first month, with gradual increases in dosage each month to a target dose of 2.4 mg weekly by the fifth month. To minimize the potential for side effects impacting daily activities, youth in the semaglutide group will be instructed to administer the medication weekly on Fridays.
Children's Hospital Los Angeles, Los Angeles
Children's Hospital Los Angeles
OTHER