Early Re-Initiation of Semaglutide Post Sleeve Gastrectomy in Youth

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

November 1, 2030

Study Completion Date

November 1, 2033

Conditions
Pediatric ObesityMetabolic and Bariatric SurgerySemaglutide
Interventions
DRUG

Semaglutide 2.4 mg

The dosing regimen will follow standard titration protocols, starting with a dose of 0.25 mg weekly for the first month, with gradual increases in dosage each month to a target dose of 2.4 mg weekly by the fifth month. To minimize the potential for side effects impacting daily activities, youth in the semaglutide group will be instructed to administer the medication weekly on Fridays.

Trial Locations (1)

90027

Children's Hospital Los Angeles, Los Angeles

All Listed Sponsors
lead

Children's Hospital Los Angeles

OTHER