Subcortical Arousal in Perceptual Awareness

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

October 13, 2025

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2030

Conditions
Epilepsy
Interventions
DEVICE

EEG

Participants will have scalp EEG recorded with the international 10-20 system sampled at 256Hz using EEG amplifiers for purposes of surface event related potential analysis

DEVICE

Eye Tracking

An eye-tracking device may be used during the perceptual awareness task. Pupillary and gaze location measurements are recorded using either a ViewPoint\~VoltagePro.EyeLink 1000 Plus system, or Argus Science ETVision system. If using the ViewPoint\~VoltagePro system or the Argus Science ETVision system, participants will be asked to wear an eye tracker during the perceptual awareness task (similar to wearing sunglasses). If using the EyeLink 1000 Plus system, participants may be asked to place their head inside of a padded head-chin rest to stabilize head position

DEVICE

Behavioral task

For the visual perceptual awareness task, the participant will be presented with barely perceptible visual stimuli. After a variable delay, the participant will be asked to report perception of each stimulus and identify its location.

Trial Locations (8)

15260

NOT_YET_RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

37235

RECRUITING

Vanderbilt University Medical Center, Nashville

55901

NOT_YET_RECRUITING

Mayo Clinic, Rochester

66160

NOT_YET_RECRUITING

University of Kansas Medical Center, Kansas City

77030

NOT_YET_RECRUITING

Baylor College of Medicine, Houston

06520

RECRUITING

Yale School of Medicine, New Haven

02114

NOT_YET_RECRUITING

Massachusetts General Hospital, Boston

03756

NOT_YET_RECRUITING

Dartmouth Hitchcock Medical Center, Lebanon

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Yale University

OTHER