A Study Evaluating the Effect of Aumolertinib on the Pharmacokinetics of Midazolam in Patients With NSCLC

PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 20, 2025

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Non Small Cell Lung Cancer
Interventions
DRUG

Aumolertinib;midazolam

"Midazolam :~The enrolled subjects will receive a single oral dose of Midazolam 2 mg (2 mg/mL, 1 mL) on D1 of the run-in period and on C2D1.~Aumolertinib :~Starting from C1D1, the enrolled subjects will receive oral dose of aumolertinib 110 mg (55 mg/tablet, 2 tablets) once daily until the criteria for terminating treatment are met."

Trial Locations (1)

310003

RECRUITING

Ethics Committee of the First Addiliated Hospital, College of Medicine, Zhejiang University, Hangzhou

All Listed Sponsors
lead

Jiangsu Hansoh Pharmaceutical Co., Ltd.

INDUSTRY