110
Participants
Start Date
April 30, 2025
Primary Completion Date
April 1, 2027
Study Completion Date
April 1, 2028
Placebo plus immunosuppression
"Participants in this arm will receive placebo plus standard immunosuppressive therapy consisting of:~Azathioprine (2.5 mg/kg/day, maximum 200 mg/day, oral) Methylprednisolone (0.5 mg/kg/day, oral, tapered over 12 weeks according to protocol) This intervention represents the standard treatment for venous thrombosis associated with Behçet's Disease and serves as the control arm of the study."
Rivaroxaban plus immunosupression
"Participants in this arm will receive standard immunosuppressive therapy as described above, plus Rivaroxaban (20 mg/day, oral, for 12 months).~This intervention aims to evaluate whether the addition of oral anticoagulation (Rivaroxaban) to immunosuppressive therapy reduces the risk of thrombotic relapse and post-thrombotic syndrome compared to immunosuppressive therapy alone."
Marmara University, School of Medicine, Division of Rheumatology, Istanbul
Marmara University, Istanbul
Lead Sponsor
Health Institutes of Turkey
OTHER_GOV
Marmara University
OTHER