Adaptive Therapy for Resected Stage ⅠA2-Ⅱ NSCLC Patients With Undetectable MRD

NARecruitingINTERVENTIONAL
Enrollment

286

Participants

Timeline

Start Date

April 6, 2025

Primary Completion Date

June 15, 2029

Study Completion Date

December 31, 2029

Conditions
NSCLC
Interventions
DRUG

Standard Therapy

For patients with negative EGFR/ALK mutation, adjuvant chemotherapy or adjuvant chemotherapy combined with immunotherapy was administered, for patients with positive EGFR/ALK mutation, targeted therapy was administered.

OTHER

Adaptive Therapy

Patients will be under close MRD and imaging monitoring without adjuvant therapy if the MRD was negative.

Trial Locations (1)

100142

RECRUITING

Peking University Cancer Hospital & Institute, Beijing

All Listed Sponsors
collaborator

Tianjin Chest Hospital

OTHER

collaborator

Peking University First Hospital

OTHER

collaborator

The First Hospital of Jilin University

OTHER

collaborator

Beijing Friendship Hospital

OTHER

collaborator

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

collaborator

Liaoning Cancer Hospital & Institute

OTHER

collaborator

Geneplus-Beijing Co. Ltd.

INDUSTRY

lead

Peking University Cancer Hospital & Institute

OTHER