ctDNA Guided Adjuvant Treatment With Elacestrant: TBCRC-068

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
ER+ Breast Cancer
Interventions
DRUG

Elacestrant

"Administration of elacestrant will follow the FDA approved dose and schedule for patients with ER+ metastatic breast cancer. Elacestrant 345 mg will be administered orally once daily for 12 cycles or until disease progression or unacceptable toxicity. The pills shall be administered with food (to reduce nausea and vomiting) at approximately the same time each day, and the prescription will be provided with the standard Swallow tablets whole; do not chew, crush, or split warning label."

Trial Locations (1)

06510

RECRUITING

Yale University, New Haven

All Listed Sponsors
collaborator

Johns Hopkins University

OTHER

collaborator

Stemline Therapeutics, Inc.

INDUSTRY

lead

Yale University

OTHER

NCT06923527 - ctDNA Guided Adjuvant Treatment With Elacestrant: TBCRC-068 | Biotech Hunter | Biotech Hunter