Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

NARecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

April 30, 2025

Primary Completion Date

April 9, 2026

Study Completion Date

May 31, 2026

Conditions
Weaning Invasive Mechanical VentilationWeaning-induced Pulmonary EdemaWeaning Failure of Mechanical VentilationSpontaneous Breathing TestIntensive Care Units (ICUs)
Interventions
DIAGNOSTIC_TEST

No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial

The spontaneous breathing test is carried out with the patient connected to the ventilator, reducing both the positive end-expiratory pressure (PEEP) and the pressure support to 0 cmH2O, for 15 minutes.

DIAGNOSTIC_TEST

Pressure Support Spontaneous Breathing trial

The spontaneous breathing test is carried out with the patient connected to the ventilator, reducing the positive end-expiratory pressure (PEEP) to 0 cmH2O and the pressure support to 7 cmH2O, for 15 minutes. A 10-minute washout period is left before the start of the next SBT modality.

DIAGNOSTIC_TEST

Humidified High Flow Spontaneous Breathing Trial

The spontaneous breathing trial is carried out with humidified high flow ventilator mode set at 50 liters per minute for 15 minutes. The patient will be connected to the ventilator via a specific connector enabling the administration of humidified high flow. A 10-minute washout period is left before the start of the next SBT modality.

Trial Locations (1)

45067

RECRUITING

Chu Orleans, Orléans

All Listed Sponsors
lead

Centre Hospitalier Régional d'Orléans

OTHER