STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

NARecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

October 17, 2025

Primary Completion Date

September 1, 2028

Study Completion Date

September 1, 2028

Conditions
Tobacco UseSubstance Use Disorders
Interventions
BEHAVIORAL

Switching to E-Cigarette

Participants will receive twelve weeks of e-cigarette products with instructions to switch completely at switch date

DRUG

Quitting using Medication

Participants will receive twelve weeks of FDA approved medication, combination NRT, with instructions to quit smoking cigarettes at quit date

BEHAVIORAL

Counseling

Participants will recieve brief weekly counseling to support their quit or switch attempt from cigarettes.

Trial Locations (3)

29425

RECRUITING

MUSC Charleston, Center for Drug and Alcohol Problems, Charleston

29526

RECRUITING

Shoreline Behavioral Health Services, Conway

29671

RECRUITING

Behavioral Health Services of Pickens County, Pickens

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Medical University of South Carolina

OTHER