The Biomechanical Outcomes of Autologous Chondrocyte Implantation

RecruitingOBSERVATIONAL
Enrollment

47

Participants

Timeline

Start Date

April 22, 2024

Primary Completion Date

September 8, 2025

Study Completion Date

January 8, 2026

Conditions
Chondral Defect
Interventions
PROCEDURE

Autologous Chondrocyte Implantation (ACI)

ACI is a two-stage process that utilises the patient's own chondrocytes to repair damaged chondral tissue. After a harvesting procedure to obtain the cells, the chondrocytes are cultured and expanded in a specialised laboratory. A second procedure is then performed to implant the cells into the defect to replace and regenerate the injured cartilage. ACI allows the knee to generate durable and hyaline-like repair tissue.

Trial Locations (7)

B31 2AP

NOT_YET_RECRUITING

Royal Orthopaedic Hospital, Birmingham

CB2 0QQ

NOT_YET_RECRUITING

Addenbrooke's Hospital, Cambridge

LS7 4SA

RECRUITING

Chapel Allerton Orthopaedic Centre, Leeds

M415SL

RECRUITING

Trafford General Hospital, Manchester

SO16 6YD

NOT_YET_RECRUITING

Southampton General Hospital, Southampton

HA7 4LP

RECRUITING

Royal National Orthopaedic Hospital, Stanmore

WV10 0QP

RECRUITING

New Cross Hospital, Wolverhampton

All Listed Sponsors
lead

University of Manchester

OTHER