Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

June 30, 2027

Conditions
Syphilis, Congenital
Interventions
DRUG

Linezolid (LZD)

Ten day course. Oral Linezolid dosed at 10mg/kg twice a day.

DRUG

Amoxicillin

Ten day course. Oral Linezolid dosed at 50mg/kg twice a day.

DRUG

Benzathine Penicillin G

Single IM dose 50,000iu/kg

Trial Locations (3)

Unknown

Universitas Indonesia, Jakarta

Malawi Liverpool Wellcome Programme, Blantyre

Stellenbosch, Stellenbosch

Sponsors
All Listed Sponsors
collaborator

University College Dublin

OTHER

collaborator

University of Stellenbosch

OTHER

collaborator

Malawi Liverpool Wellcome Programme

OTHER

collaborator

University of Sydney

OTHER

collaborator

Murdoch Childrens Research Institute

OTHER

collaborator

MRC CTU at UCL

UNKNOWN

collaborator

PHPT/AMS Laboratory, Faculty of Associated Medical Sciences, Chiang Mai University

UNKNOWN

lead

London School of Hygiene and Tropical Medicine

OTHER

NCT06921213 - Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis | Biotech Hunter | Biotech Hunter