300
Participants
Start Date
May 1, 2025
Primary Completion Date
March 31, 2027
Study Completion Date
March 31, 2027
Ertapenem
Participants will receive a single dose of IV ertapenem (1g) in the operating room prior to incision or as soon as possible given the patient's hemodynamic status
Cefazolin and Metronidazole.
Participants will receive a single dose of a combination of IV cefazolin (re-dosed during the case every 4 hours and/or after every 1,500 mL of blood loss) and IV metronidazole (single dose 500 mg) in the operating room prior to incision or as soon as possible given the patient's hemodynamic status
The University of Texas Health Science Center at Houston, Houston
Surgical Infection Society
UNKNOWN
The University of Texas Health Science Center, Houston
OTHER