NCT06917404View on ClinicalTrials.gov

A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.

PHASE3RecruitingINTERVENTIONAL
Enrollment

466

Participants

Timeline

Start Date

May 29, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2027

Conditions
Osteoarthritis, Knee
Interventions
DRUG

Pentosan Polysulfate Sodium twice weekly

Subcutaneous injection, 2 mg/kg twice weekly for 6 weeks

DRUG

Placebo

Placebo, subcutaneous injection, twice weekly for 6 weeks

Trial Locations (3)

3128

RECRUITING

Sportsmed Biologic LTD, Box Hill

32789

RECRUITING

Conquest Research, Winter Park

68516

RECRUITING

Physician Research Collaboration, Lincoln

Sponsors
All Listed Sponsors
lead

Paradigm Biopharmaceuticals Ltd.

INDUSTRY