60
Participants
Start Date
May 1, 2025
Primary Completion Date
May 31, 2026
Study Completion Date
May 31, 2027
Administration of antibiotics prophylactically at the time of membrane rupture
"Participants will receive the antibiotic regimen:~* Day 1: Oral Azithromycin 1 g once and intravenous Ampicillin 2 g every 6 hours~* Day 2: Intravenous Ampicillin 2 g every 6 hours~* Days 3-7: Oral Amoxicillin 500 mg every 8 hours"
Administration of antibiotics non-prophylactically at 22 weeks
"Participants will receive latency antibiotics starting 22 weeks 0 days:~* Day 1: Oral Azithromycin 1 g once and intravenous Ampicillin 2 g every 6 hours~* Day 2: Intravenous Ampicillin 2 g every 6 hours~* Days 3-7: Oral Amoxicillin 500 mg every 8 hours"
The University of Texas Health Science Center at Houston, Houston
The University of Texas Health Science Center, Houston
OTHER