Neoadjuvant SNF Precision Therapy Phase III

PHASE3RecruitingINTERVENTIONAL
Enrollment

404

Participants

Timeline

Start Date

April 8, 2025

Primary Completion Date

October 15, 2026

Study Completion Date

April 15, 2027

Conditions
Neoadjuvant Therapy
Interventions
DRUG

Targeted therapy agents: SNF2 -adebrelimab + famitinib; SNF3 -fluzoparib; SNF4 -apatinib

The backbone is chemotherapy which will be used in the control group. The precision group will add targeted therapy agents which were determined according to SNF classification: the SNF2 subtype add adebrelimab combined with famitinib, the SNF3 subtype receives fluzoparib, and the SNF4 subtype receives apatinib.

DRUG

Chemotherapy (wP-EC)

Chemotherapy : weely nab-P \* 12- EC \* 4

Trial Locations (1)

200032

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER