GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

September 15, 2024

Primary Completion Date

September 15, 2026

Study Completion Date

February 15, 2027

Conditions
Irritable Bowel Syndrome (IBS)Genome-wide Association StudySingle Nucleotide PolymorphismsMediterranean DietFODMAP Diet
Interventions
OTHER

Med-LFD intervention

In the beginning of the intervention, blood and stool samples will be collected. All participants of the group at phase 1 (elimination phase), will initially follow the Med- LFD (2-6 weeks). At phase 2 (reintroduction phase), patients will gradually reintroduce foods rich in FODMAPs (6-8 weeks) and test their tolerance. At phase 3 (maintenance phase), following the reintroduction of foods rich in FODMAPs, patients will follow an individualized diet based on their personal tolerance (a combination of high and low FODMAPs). In the end of intervention, stool samples will be collected again.

Trial Locations (1)

12462

RECRUITING

Attikon General University Hospital of Athens, Athens

All Listed Sponsors
lead

Attikon Hospital

OTHER