530
Participants
Start Date
April 24, 2025
Primary Completion Date
July 31, 2028
Study Completion Date
July 31, 2028
Participants will receive Tongmai Jiangtang Capsule (TJC) in addition to standard treatment.
"Intervention Agent: The study employs Tongmai Jiangtang Capsule (TJC), a traditional Chinese medicine compound formulated based on TCM theory. It has the functions of Nourishing Yin, clearing heat and activating blood circulation, and can comprehensively regulate glucose and lipid metabolism as well as improve cardiovascular and cerebrovascular functions.~Intervention Population: The study focuses on patients with metabolic syndrome at high cardiovascular and cerebrovascular risk (HCR-MS) who meet the TCM criteria for Qi-deficiency and Blood Stasis syndrome, reflecting personalized and precision intervention.~Intervention Design: A long-term study design with 26 weeks of intervention followed by 26 weeks of follow-up is adopted to comprehensively assess the short-term efficacy and long-term cardiovascular benefits of TJC.~Control Design: The study employs a double-blind, randomized, placebo-controlled method."
A placebo capsule that is identical in appearance, size, color, formulation, weight, taste, and smell to TJC
Participants in this Arm will receive a placebo capsule that is identical in appearance, size, color, formulation, weight, taste, and smell to TJC, in addition to standard treatment.
Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou
TCM hospital of Sichuan Province
UNKNOWN
Xiyuan Hospital of CACMS
UNKNOWN
Shanxi Provincial hospital of Chinese Medicine
UNKNOWN
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
OTHER
The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
OTHER
Yinchuan Brain-Heart Simultaneous Treatment Internet Hospital Co., Ltd
UNKNOWN
Guangdong Provincial Hospital of Traditional Chinese Medicine
OTHER