NCT06908265View on ClinicalTrials.gov

Clinical Evaluation of the Antibacterial Activity of Thioglycosides Extracted from White Mustard - Bamberka in Oral Hygiene. Evaluation of Periodontal Parameters and Oral Microbiota in Patients.

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

113

Participants

Timeline

Start Date

March 31, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

January 31, 2017

Conditions
Gingival and Periodontal DiseaseCaries, Dental
Interventions
DRUG

Toothpaste including mustard extract

"Intervention: Herbal toothpaste containing 0.5% white mustard (Sinapis alba) extract. To assess its effect on plaque index (PI), approximal plaque index (API), gingival index (GI), bleeding on probing (BoP), and bacterial loads of Streptococcus mutans and Lactobacillus spp.~Dosage and Usage: Participants brush their teeth twice daily for 4 weeks with the assigned toothpaste."

DRUG

Placebo

"lacebo toothpaste, formulated identically to the experimental toothpaste but without white mustard extract. Serves as a control to compare the antibacterial and clinical effects of the herbal toothpaste.~Dosage and Usage: Participants brush their teeth twice daily for 4 weeks with the placebo toothpaste."

All Listed Sponsors
lead

Medical University of Warsaw

OTHER

NCT06908265 - Clinical Evaluation of the Antibacterial Activity of Thioglycosides Extracted from White Mustard - Bamberka in Oral Hygiene. Evaluation of Periodontal Parameters and Oral Microbiota in Patients. | Biotech Hunter | Biotech Hunter