A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

June 30, 2029

Study Completion Date

June 30, 2029

Conditions
Knee OsteoarthritisDepression
Interventions
DEVICE

repetetive transcranial magnetic stimulation

rTMS treatments will be performed with the MagVenture MagPro X100 stimulator equipped with the Cool-B70 A/P for sham-controlled stimulation. The coil has two sides, one of which is shielded so that no energy is imparted to the brain when the shielded side is applied to the subject's head. Small skin electrodes are applied to the scalp under the coil that impart a small microcurrent to the scalp simulating the sensation of active treatment. The operator receives a code from the device instructing them which side of the coil to use for each subject, ensuring complete treatment blinding.

Trial Locations (1)

90095

UCLA Semel Institute - Neuropsychiatric Institute (NPI), Los Angeles

All Listed Sponsors
lead

University of California, Los Angeles

OTHER