Dexamethasone Treatment for Patients Undergoing Endodontics

PHASE4CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

November 4, 2024

Primary Completion Date

December 27, 2024

Study Completion Date

January 31, 2025

Conditions
Endodontic TreatmentPulp NecrosisPeriapical LesionsPostoperative Pain
Interventions
DRUG

Dexamethasone 4 mg

Participants in this group received a single 4 mg oral dose of dexamethasone 1 hour before undergoing endodontic treatment. No additional preoperative analgesics were administered. Standard endodontic procedures, including local anesthesia, were performed. Post-treatment, no routine analgesic medication was provided unless additional pain relief was required. Pain intensity was assessed at 4, 6, 8, 12, and 24 hours using the Visual Analog Scale (VAS) to evaluate the efficacy of preoperative dexamethasone in controlling postoperative pain and inflammation.

DRUG

Ibuprofen group

Participants in this group received no preoperative medication but were prescribed 400 mg of ibuprofen every 4 hours postoperatively for pain management. The same standard endodontic procedures were performed. Pain levels were recorded at 4, 6, 8, 12, and 24 hours using the VAS scale to compare the effectiveness of postoperative ibuprofen with preoperative dexamethasone.

Trial Locations (1)

37008

University of Salamanca, Salamanca

All Listed Sponsors
lead

University of Salamanca

OTHER

NCT06906315 - Dexamethasone Treatment for Patients Undergoing Endodontics | Biotech Hunter | Biotech Hunter