Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children

PHASE3RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

April 30, 2029

Study Completion Date

April 30, 2029

Conditions
Lupus Nephritis
Interventions
BIOLOGICAL

Low-dose CAR-T cells group

This group of patients received low dose novel structure of Chimeric Antigen Receptors T (CAR-T) cells therapy with an infusion dose of approximately 5×100,000 cells/Kg.

BIOLOGICAL

High-dose CAR-T cells group

This group of patients received high dose novel structure of Chimeric Antigen Receptors T (CAR-T) cells therapy with an infusion dose of approximately 1×1000,000 cells/Kg.

Trial Locations (1)

510000

RECRUITING

Guangzhou Women and Children Medical Center, Guangzhou

All Listed Sponsors
lead

Guangzhou Women and Children's Medical Center

OTHER