Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

PHASE2RecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

August 13, 2025

Primary Completion Date

February 24, 2027

Study Completion Date

February 25, 2030

Conditions
aGVHDAcute Myelogenous LeukemiaAcute Lymphocytic LeukemiaMyelodysplastic Syndromes
Interventions
BIOLOGICAL

Haplo-Identical / Cord Blood Transplant

"Cord Blood Unit Selection Cord Blood Unit Selection should be consistent with published guidelines5 with the understanding that the goal cell dose is 1x105 CD34 cells/kg in this protocol. ABO matching and donor specific antibodies should be taken into account in the selection of the CB unit.~Haplo-Donor Selection Haplo-identical siblings and younger male donors are preferred. ABO matching, CMV compatibility, and donor specific antibodies should be taken into account in the selection of the donor."

Trial Locations (1)

44106

RECRUITING

Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center Seidman Cancer Center, Cleveland

All Listed Sponsors
lead

Case Comprehensive Cancer Center

OTHER