90
Participants
Start Date
October 15, 2025
Primary Completion Date
May 31, 2027
Study Completion Date
May 31, 2028
Ketamine
Participants in this group will receive a single intravenous (IV) dose of ketamine at 0.5 mg/kg, administered within 30 minutes of anesthesia induction during surgical fixation for musculoskeletal trauma. The purpose of the intervention is to evaluate ketamine's effect on postoperative pain, opioid consumption, and psychological recovery, including symptoms of depression and post-traumatic stress disorder (PTSD).
standard general anesthesia
Participants in this group will receive standard general anesthesia during surgical fixation for musculoskeletal trauma. No ketamine will be administered. This group serves as a comparison to evaluate the effects of ketamine on pain, opioid use, and psychological recovery.
Texas Tech University Health Sciences Center Lubbock, Lubbock
University Medical Center, Lubbock
Texas Tech University Health Sciences Center
OTHER