A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

April 14, 2025

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2026

Conditions
MASH
Interventions
DRUG

RO7790121

Participants will be administered RO7790121 via IV infusion on Day 1, and Weeks 2, 6 and 10. Participants will then be administered RO7790121 SC injections every four weeks (Q4W) from week 14 up to and including Week 50.

Trial Locations (25)

14090

Inovacion y Desarrollo en ciencias de la salud, Ciudad de Mxico

27000

CIMAB S.A. de C.V., Torreón

30060

Gastrointestinal Specialists of Georgia, PC, Marietta

31203

Mediadvance Clinical SAPI De CV, Chihuahua City

33176

Gastro Health Research - Miami, Miami

37040

Premier Medical Group Int Medcn, Clarksville

38018

Gastroenterology Center of the MidSouth PC, Cordova

44340

Centro de Investigacion Clinica y Medicina Traslacional CIMeT, Guadalajara

45170

Hospital General de Occidente SSJ, Zapopan

58249

Clínica de Enfermedades Crónicas y de Procedimientos Especiales, S.C (CECYPE), Morelia

66278

Centro Médico Zambrano Hellion, San Pedro Garza García

71220

Delta Research Partners, LLC (Bastrop), Bastrop

76092

GI Alliance, Southlake

77079

Houston Research Institute, Houston

77401

Bellaire Clinical Research, LLC, Bellaire

78229

Pinnacle Clinical Research, PLLC, San Antonio

78539

DHR Health Institute for Research and Development, Edinburg

78626

Pinnacle Clinical Research Georgetown, Georgetown

78757

Pinnacle Clinical Research - Austin, Austin

85712

Adobe Clinical Research, LLC, Tucson

89106

Jubilee Clinical Research, Inc, Las Vegas

98004

GI Alliance, Bellevue

06700

Centro de Investigacion y Gastroenterologia, Mexico City

00680

FDI Clinicial Research - Mayaguez, Mayagez

00927

Fundacion de Investigacion de Diego, San Juan

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY