A Phase 2 Trial in Healthy Adult Participants of the Recombinant MVA-BN-WEV Vaccine

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

411

Participants

Timeline

Start Date

March 10, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

March 31, 2027

Conditions
Encephalitis
Interventions
BIOLOGICAL

MVA-BN-WEV

MVA-mBN396 (common name MVA-BN-WEV vaccine), is a highly attenuated, live recombinant virus based on the licensed viral vector MVA-BN, provided as a liquid frozen formulation. It is administered as an intramuscular injection.

OTHER

Placebo

Tris-Buffered Saline (TBS) (placebo) is a clear liquid, free from visible extraneous particles. TBS is acceptable for use as a diluent and for intramuscular injection.

Trial Locations (9)

30047

Lifeline Primary Care, Inc. / CCT Research, Lilburn

40383

Versailles Family Medicine, PLLC/CCT Research, Versailles

64151

Clay-Platte Family Medicine, P.C./CCT Research, Kansas City

65109

Jefferson City Medical Group / Avacare, Jefferson City

66219

Johnson County Clin-Trials, Lenexa

68046

Papillion Research Center/CCT Research, Papillion

70065

Benchmark Research, Kenner

76904

Benchmark Research, San Angelo

95864

Benchmark Research, Sacramento

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

JPM CBRN Medical

UNKNOWN

lead

Bavarian Nordic

INDUSTRY

NCT06899802 - A Phase 2 Trial in Healthy Adult Participants of the Recombinant MVA-BN-WEV Vaccine | Biotech Hunter | Biotech Hunter