Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

November 24, 2025

Study Completion Date

December 24, 2025

Conditions
Motor ImpairmentMotor ImpairmentsStrokeStroke; SequelaeStroke, Ischemic
Interventions
DEVICE

Transcutaneous auricular vagus nerve stimulation + rehabilitation therapy

Transcutaneous auricular vagus nerve stimulation using INPULSE 3 times a week for six consecutive weeks. The stimulation parameters will be a frequency of 30Hz with a pulse width of 300 us and a stimulation time of 1.5 seconds for each respiratory cycle. The electrical current will be gradually increased to a maximum of 5 mA (0.25-mA increments) to allow adaptation to the stimulation until a comfortable tolerance level is achieved. Patients will receive physical rehabilitation therapy during stimulation, which will include reaching and grasping exercises, gross movements, turning objects, simulating specific tasks, inserting objects, opening and closing containers.

OTHER

sham stimulation + rehabilitation therapy

Patients will receive physical rehabilitation therapy during placebo stimulation (No electrical stimulation), including reaching and grasping exercises, gross movements, turning objects, simulating specific tasks, inserting objects, opening and closing containers.

Trial Locations (1)

Unknown

Neurology Center of Excellence - Hospital Internacional de Colombia - Fundación cardiovascular de Colombia, Piedecuesta

All Listed Sponsors
collaborator

Ministerio de Ciencia Tecnología e Innovación - Minciencias

UNKNOWN

lead

Fundación Cardiovascular de Colombia

OTHER

NCT06895005 - Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke | Biotech Hunter | Biotech Hunter