Oral Tranexamic Acid After Total Knee Arthroplasty

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

351

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

March 1, 2026

Study Completion Date

June 1, 2026

Conditions
Total Knee Arthroplasty
Interventions
DRUG

tranexamic acid Oral-Short Arm

1.95g Tranexamic acid daily for post op days 1 to 3

DRUG

tranexamic acid Oral-Long Arm

1.95g tranexamic acid daily post op days 1-7

DRUG

Control group placebo

Placebo for 3 days post-op

All Listed Sponsors
lead

Rush University Medical Center

OTHER