Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment

NARecruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

December 18, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
Migraine, Greater Occipital Nerve Pulsed RadiofrequencyHeadache DisordersUltrasound Guided Nerve Block
Interventions
OTHER

Greater Occipital Nerve Pulsed Radiofrequency (Unilateral)

Greater Occipital Nerve (GON) Pulsed Radiofrequency (PRF) treatment is performed under sterile conditions in the operating room. The patient is positioned in the prone position with neck flexion. Under ultrasound guidance at the proximal (C2) level, the needle is carefully placed near the GON, targeting the space between the Obliquus Capitis Inferior (OCI) muscle and C2's bifid spinous process. After proper sterilization, a linear ultrasound probe is used transversely over the occipital protuberance to locate the C1 and C2 vertebrae. Once identified, the RF needle and electrode are inserted laterally to medially using in-plane technique. A sensory stimulation test is done, and the PRF therapy is applied at a 45V setting, 5 Hz, and 5 ms pulse width for 360 seconds, with a maximum temperature of 42°C. No drug injections are administered during the procedure. Post-procedure, the patient is monitored for at least 1 hour before discharge after a general and neurological evaluation.

OTHER

Bilateral GON PRF Treatment:

"Greater Occipital Nerve (GON) Pulsed Radiofrequency (PRF) treatment is performed under sterile conditions in the operating room. The patient is positioned in the prone position with neck flexion. Under ultrasound guidance at the proximal (C2) level, the needle is carefully placed near the GON, targeting the space between the Obliquus Capitis Inferior (OCI) muscle and C2's bifid spinous process. After proper sterilization, a linear ultrasound probe is used transversely over the occipital protuberance to locate the C1 and C2 vertebrae. Once identified, the RF needle and electrode are inserted laterally to medially using in-plane technique. A sensory stimulation test is done, and the PRF therapy is applied at a 45V setting, 5 Hz, and 5 ms pulse width for 360 seconds, with a maximum temperature of 42°C. No drug injections are administered during the procedure. Post-procedure, the patient is monitored for at least 1 hour before discharge after a general and neurological evaluation.~Bilater"

Trial Locations (2)

06800

RECRUITING

Health Sciences University, Ankara Bilkent City Hospital, Ankara

RECRUITING

Health Sciences University, Ankara Bilkent City Hospital, Ankara

All Listed Sponsors
lead

Ankara City Hospital Bilkent

OTHER