Individualized Comprehensive Treatment for Advanced Hepatocellular Carcinoma

FOLFOX4 was administered by oxaliplatin 85 mg/m² d1+ leucovorin 200 mg/m² d1-2+ fluorouracil 400 mg/m² 2 h→ 600 mg/m² 24 h d1-2 q2w, with a total of 4 cycles

Adebrelimab 1200mg, intravenous infusion, every 3 weeks

Apatinib 250mg, oral, once daily.

Epimedium extract soft capsules 2.4g, oral, 2 times daily.

SHR1701，30mg/kg, intravenous infusion, every 3 weeks, use for up to 2 years at most.

QL1706，5mg/kg, intravenous infusion, every 3 weeks, use for up to 2 years at most.

Bevacizumab 7.5mg, intravenous infusion, once every 3 weeks.

Hepatic Arterial Infusion Chemotherapy

Local treatment of oligo-metastases.

Continue the original targeted therapy combined with immunotherapy. dosage, dosage form,frequency of administration was the same as before.