QL1706 Combined With Lenvatinib and GEMOX as First - Line Treatment for Unresectable Biliary Tract Tumors

PHASE2RecruitingINTERVENTIONAL
Enrollment

59

Participants

Timeline

Start Date

June 14, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2029

Conditions
Biliary Tract Tumors
Interventions
DRUG

QL1706

Eligible participants will receive QL1706 at 5.0 mg/kg intravenously every 3 weeks, lenvatinib at 8 mg orally once daily every 3 weeks, oxaliplatin at 85 mg/m², and gemcitabine at 1000 mg/m² (on days 1 and 8 of each cycle) for up to 8 cycles. Then, they will continue with QL1706 and lenvatinib until clinical progression, imaging progression per RECIST 1.1, unacceptable toxicity, withdrawal of consent, or other discontinuation criteria are met.

Trial Locations (1)

200433/201805

RECRUITING

the Third Affiliated Hospital of Naval Medical University, Shanghai

All Listed Sponsors
lead

Eastern Hepatobiliary Surgery Hospital

OTHER

NCT06892925 - QL1706 Combined With Lenvatinib and GEMOX as First - Line Treatment for Unresectable Biliary Tract Tumors | Biotech Hunter | Biotech Hunter