Efficacy and Safety of tACS for Depression: a Multicenter RCT Study

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

October 8, 2024

Primary Completion Date

September 8, 2025

Study Completion Date

October 8, 2026

Conditions
Depression Disorders
Interventions
DEVICE

sham transcranial Alternating Current Stimulation

we use fade-in, short-stimulation, fade-out (FSF) stimulation pattern, with 60s-long fade-in/out periods, 2.0mA peak current at the beginning and the end of stimulation session

DEVICE

active tACS

The active tACS protocol lasted for 40 min of continuous sine-wave stimulation with the frequency of 10Hz and an amplitude ranging from 1.5mA to 2.0mA, adjusted according to the tolerability among individuals.

Trial Locations (2)

200025

NOT_YET_RECRUITING

Ruijin Hospital affiliated to Shanghai JiaoTong University School of Medicine, Shanghai

RECRUITING

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
collaborator

Shanghai Mental Health Center

OTHER

collaborator

Shandong Mental Health Center

OTHER

lead

Ruijin Hospital

OTHER