Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia

NARecruitingINTERVENTIONAL
Enrollment

174

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

September 30, 2026

Conditions
Zoster; Herpes, Trigeminal Neuralgia (Etiology)
Interventions
DRUG

Esketamine group

Patients in the esketamine group will receive intravenous infusion of esketamine besides PRF+standardized treatment.The formula will be intravenous infusion of 0.5mg/kg of esketamine diluted in 50 mL normal saline, starting with intravenous injection of 10 mg of esketamine for 1 minute, and maintaining a dose 8 mg/h.The infusion rate will be adjusted the parameter according to the tolerance of the patients

DRUG

PRF group

Patients in the control group will receive PRF+standardized treatment

Trial Locations (1)

100050

RECRUITING

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
collaborator

Beijing Xiaotangshan Hospital

OTHER

collaborator

The First Hospital of Fangshan District,Beijing

OTHER

collaborator

Beijing Ditan Hospital

OTHER

collaborator

Hengshui People's Hospital

OTHER

lead

Beijing Tiantan Hospital

OTHER