The Anti-Anginal Effects of N-Acetylcysteine (NAC) in Patients with Angina and Non-Obstructive Coronary Arteries (ANOCA)

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

April 1, 2027

Study Completion Date

September 1, 2027

Conditions
Angina AttacksNon Obstructive Coronary Artery Disease
Interventions
DRUG

N-Acetylcysteine (NAC)

The investigational product for this study is NAC 600 mg capsules. The NAC drug substance is sourced from a Good Manufacturing Practice (GMP)-certified supplier by Syntro Health Pty Ltd and tested on receipt

DRUG

Placebo

To ensure appropriate blinding and to match the physical characteristics of the NAC capsules, the placebo capsules will be filled with dicalcium phosphate (DCP). DCP has been selected over microcrystalline cellulose due to the weight requirements of the NAC formulation.

Trial Locations (1)

5011

The Queen Elizabeth Hospital, Adelaide

All Listed Sponsors
lead

University of Adelaide

OTHER

NCT06890507 - The Anti-Anginal Effects of N-Acetylcysteine (NAC) in Patients with Angina and Non-Obstructive Coronary Arteries (ANOCA) | Biotech Hunter | Biotech Hunter