30
Participants
Start Date
March 8, 2025
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2027
Neoadjuvant chemoradiotherapy combined with PD-1/PD-L1 inhibitors for the treatment of locally advanced resectable esophageal squamous cell carcinoma
Toripalimab: intravenous infusion, 240mg, D1, Q3W, for 2 consecutive doses; or Envorimab: subcutaneous injection, 400mg, D1, Q3W, for 2 consecutive doses. Albumin-bound paclitaxel: intravenous infusion, 50mg/m2, D1, QW, for 5 consecutive doses. Carboplatin: intravenous infusion, AUC=2, D1, QW, for 5 consecutive doses. Radiotherapy: 41.4Gy/1.8Gy/23F, D1-5, 5 times per week.
Henan Cancer Hospital, Zhengzhou
The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital
UNKNOWN
Henan Cancer Hospital
OTHER_GOV