NCT06887621View on ClinicalTrials.gov

Efficacy of Adding Oral Amisulpride to Dual Prophylaxis for Postoperative Nausea and Vomiting in Patients at High Risk for Nausea and Vomiting Undergoing Gynecological Surgery

PHASE2RecruitingINTERVENTIONAL
Enrollment

276

Participants

Timeline

Start Date

April 10, 2025

Primary Completion Date

March 29, 2027

Study Completion Date

March 31, 2027

Conditions
Post Operative Nausea and Vomiting (PONV)
Interventions
DRUG

Encapsulated amisulpride 50 mg (matched for color, weight, smell and size)

Amisulpride will be delivered orally 1 hour before anesthesia induction.

DRUG

Encapsulated placebo (matched for color, weight, smell and size)

Placebo will be delivered orally 1 hour before anesthesia induction.

Trial Locations (1)

Unknown

RECRUITING

Hospital da Mulher, São Paulo

All Listed Sponsors
collaborator

University Medical Center Groningen

OTHER

lead

Instituto do Cancer do Estado de São Paulo

OTHER