Efficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 6, 2024

Primary Completion Date

November 1, 2025

Study Completion Date

November 30, 2025

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG

Adebrelimab: 20mg/kg day1, Q3W, 3 times

Concurrent Chemoradiotherapy combined with Immunotherapy,including: Radiotherapy: intensity modulated radiotherapy, PGTV 50-50.4Gy/25-28F, 1.8-2Gy/F, 5 times a week; Chemotherapy: paclitaxel 50mg/ m2 + cisplatin 25mg/ m2, intravenous infusion of day1, once a week, a total of 5 times; Adebrelimab: 20mg/kg day1, Q3W, 3 times.

Trial Locations (1)

Unknown

RECRUITING

Nanfang Hospital, Southern Medical University, Guangzhou

All Listed Sponsors
lead

Nanfang Hospital, Southern Medical University

OTHER