a Polyphenol Whole Tumor Cell Vaccine in Patients With Advanced Malignant Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

April 21, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

December 31, 2026

Conditions
PolyphenolsCancer VaccineAdvanced Solid Tumor
Interventions
BIOLOGICAL

Polyphenol whole tumor cell vaccine

3 patients enrolled in each dose group, and planned dose groups of 5 x 10\*6, 2 x 10\*7, and 5 x 10\*7 cells/dose. The dosing regimen consisted of 5 doses of basal immunization and subsequent individualized treatment. In the basal immunization, the administration times were D0, D14, D28, D42, and D56. After completion of the 5 doses of basal immunization, the subsequent individualized treatment was decided by the investigator based on the subject's tumor assessment, i.e., 1 vaccination per month for a total of 4 doses.

Trial Locations (1)

610041

RECRUITING

West China Hospital, Sichuan Universit, Chengdu

All Listed Sponsors
lead

Xingchen Peng

OTHER