A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 17, 2025

Primary Completion Date

November 30, 2028

Study Completion Date

November 30, 2028

Conditions
Breast Cancer MetastaticLocally Advanced Breast Cancer (LABC)Malignant Neoplasm of BreastTriple Negative Breast Cancer (TNBC)Hormone Receptor-Positive Breast CancerHER2 + Breast Cancer
Interventions
BIOLOGICAL

Two Component Product CLBR001 + ABBV-461

Investigational switchable CAR-T cell therapy for breast cancer

Trial Locations (3)

14263

RECRUITING

Roswell Park Cancer Institute, Buffalo

22908

RECRUITING

University of Virginia, Charlottesville

46202

RECRUITING

Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis

All Listed Sponsors
lead

Calibr, a division of Scripps Research

OTHER