NCT06877208View on ClinicalTrials.gov

The Effect of Glucagon on Cerebral Glucose Metabolism in Healthy Humans

NANot yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

September 30, 2025

Study Completion Date

March 31, 2026

Conditions
Cerebral Glucose Metabolism
Interventions
OTHER

Glucagon (part C)

90 minutes intravenous infusion with glucagon (infusion rate of 10 ng/kg/min).

OTHER

Glucose clamp (part C)

90 minutes intravenous infusion of 20 % weight/volume glucose (in an ajustable rate to match the glucose levels achieved during the glucagon infusion).

OTHER

Saline (part C)

90 minutes intravenous infusion with isotonic NaCl.

OTHER

Glucagon (part D)

210 minutes intravenous infusion with glucagon (infusion rate of 10 ng/kg/min).

OTHER

Glucose clamp (part D)

210 minutes intravenous infusion of 20 % weight/volume glucose (in an ajustable rate to match the glucose levels achieved during the glucagon infusion).

OTHER

Saline (part D)

210 minutes intravenous infusion with isotonic NaCl.

Trial Locations (1)

2400

Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, Copenhagen

All Listed Sponsors
collaborator

Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark

UNKNOWN

lead

Nicolai Jacob Wewer Albrechtsen

OTHER