Relma-cel Followed by Tislelizumab for the Treatment of Relapsed/Refractory CNS Large B-Cell Lymphoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 30, 2023

Primary Completion Date

November 30, 2028

Study Completion Date

November 30, 2028

Conditions
CNS Lymphoma
Interventions
DRUG

Relma-cel Followed by Tislelizumab

Enrolled patients with relapsed/refractory (R/R) CNSL will receive Relma-cel infusion, followed by treatment with Tislelizumab (200mg, IV, q4w, for 12 months) starting at 35 days post-infusion. BTK inhibitors will be used in combination as needed.

Trial Locations (6)

Unknown

NOT_YET_RECRUITING

Beljing Tiantan Hospital, Capttal Medical, University, Beijing

NOT_YET_RECRUITING

Xuanwu Hospital Capital Medical University, Beijing

NOT_YET_RECRUITING

Sun Yat-Sen University Cancer Center, Guangzhou

NOT_YET_RECRUITING

Henan Cancer Hospital, Henan

RECRUITING

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

NOT_YET_RECRUITING

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,, Wuhan

All Listed Sponsors
lead

Ruijin Hospital

OTHER