Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction

NARecruitingINTERVENTIONAL
Enrollment

1,047

Participants

Timeline

Start Date

April 8, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Stroke
Interventions
DEVICE

Motor-cognitive interactive robot

Motor-cognitive interactive robot-assisted training integrates motor and cognitive rehabilitation using an upper limb rehabilitation robot. If patients cannot actively lift the robotic arm, an eye-tracking mode detects movement intention and guides the arm along predefined trajectories, adjusting motor and cognitive loads dynamically. As motor function improves, training shifts to an active mode with increased resistance. Patients complete cognitive tasks before moving the robotic arm, while the system monitors movement parameters and provides real-time feedback. Training consists of 60-minute sessions, five days per week for four weeks. Motor load progresses by increasing robotic arm speed or resistance, while cognitive load advances based on task accuracy, ensuring personalized and adaptive rehabilitation.

DEVICE

Motor-focused robot

Motor-focused robot-assisted training primarily emphasizes motor rehabilitation through the use of an upper limb rehabilitation robot. When patients are unable to actively lift the robotic arm, an eye-tracking mode is employed to guide movements, with adjustments made solely to the motor load. As motor function improves, the training transitions to an active mode, progressively increasing resistance while maintaining a constant, minimal level of cognitive difficulty. Patients are required to complete cognitive tasks before initiating movement of the robotic arm, while the system monitors key movement parameters and provides real-time feedback. Training consists of 60-minute sessions, five days per week for four weeks. Motor load is progressively increased by adjusting the speed or resistance of the robotic arm, while cognitive load remains consistently at the lowest level throughout the training.

BEHAVIORAL

Conventional rehabilitation training

Conventional rehabilitation training adheres to internationally established guidelines and employs task-oriented approaches tailored to activities of daily living (ADLs). The therapeutic regimen incorporates fundamental motor skill exercises, including but not limited to grasp-and-release maneuvers, targeted reaching, fine motor skill development (e.g., button manipulation, zipper operation), and bilateral coordination tasks (e.g., garment folding, towel wringing). The intervention protocol emphasizes progressive task difficulty and functional task integration, with each session lasting 60 minutes. The treatment schedule consists of daily sessions, five times per week, over a four-week duration.

Trial Locations (1)

350122

RECRUITING

Fujian University of Traditional Chinese Medicine, Fuzhou

Sponsors
All Listed Sponsors
collaborator

Fujian University of Traditional Chinese Medicine Affiliated Rehabilitation Hospital

UNKNOWN

collaborator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER

collaborator

China Rehabilitation Research Center

OTHER_GOV

collaborator

Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

UNKNOWN

collaborator

Shanghai Sunshine Rehabilitation Center

UNKNOWN

lead

Lidian Chen

OTHER

NCT06876597 - Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction | Biotech Hunter | Biotech Hunter