Is There a Need for Luteal Support in Modified Natural Cycle Frozen Embryo Transfer Cycles

PHASE4RecruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

April 12, 2025

Primary Completion Date

April 1, 2026

Study Completion Date

December 1, 2026

Conditions
Luteal SupportFrozen Embryo Transfer (FET)
Interventions
DRUG

no luteal support

In one arm of the study the patients receive no luteal support as part of their modified natural cycle frozen embryo transfer.

DRUG

Vaginal Progesterone

In the 2nd arm the patient receives 2x200 mg vaginal progesterone as luteal support.

DRUG

Progesterone plus HCG

In the 3rd arm the patients receive 2x200 mg vaginal progesteroen plus 125 mcg recombinant HCG s.c. on the day of embryo transfer and 62.5 mcg recombinant HCG s.c. 4 days later.

Trial Locations (5)

1125

RECRUITING

Dunamenti REK Istenhegyi IVF Center, Budapest

6723

RECRUITING

University of Szeged, Reproductive Medicine Institute, Szeged

7624

RECRUITING

University of Pecs, Dept. OBGYN, Reproductive Center, Pécs

8300

RECRUITING

Dunamenti REK Tapolca IVF Center, Tapolca

9026

RECRUITING

Dunamenti REK Gyor IVF Center, Győr

All Listed Sponsors
collaborator

Medical University of Pecs

OTHER

collaborator

Dunamenti REK Gyor Clinic

UNKNOWN

collaborator

Dunementi REK Pannon Clinic

UNKNOWN

collaborator

University of Szeged, Hungary

UNKNOWN

lead

Dunamenti REK Istenhegyi IVF Center

OTHER