Arm and Leg Cycling for Accelerated SCI Recovery

NAEnrolling by invitationINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

December 31, 2025

Primary Completion Date

March 31, 2032

Study Completion Date

September 30, 2032

Conditions
Spinal Cord Injury
Interventions
DEVICE

A&L cycling

Participants will complete simultaneous arms and legs cycling for 60min of active cycling. Targeted exercise intensity is 70-85% of the age-predicted maximum heart rate. Cycling resistance will be modified for continuous challenge. A target speed 10% above the highest speed at which each study participant is able to cycle voluntarily without motor, FES, or tSCS assistance will be selected during the first session and maintained throughout all training sessions. Once a participant can complete 60 minutes of continuous cycling at a specific resistance for two consecutive training sessions, the resistance will be increased to the next setting level at the mid-point of the subsequent session. Upon completion of each session, the physical therapists/researcher will complete skin checks to ensure no adverse effects have occurred. Heart rate, blood pressure, and oxygen saturation will be recorded. Participants will complete 3 training sessions per week for 12 weeks.

DEVICE

Body weight supported treadmill training (BWSTT)

The physical therapists/researchers will assist the patient with donning any necessary lower extremity braces and a padded walking harness. The patient will be assisted onto the treadmill via a ramp while seated in a wheelchair or by ambulation with physical assistance, clipped into the body weight support system, assisted to stand, and provided the appropriate amount of body weight support to allow for successful stepping for 60 minutes of active walking. During BWSTT, physical therapists/trainers will adjust treadmill speed or incline and the degree of body weight support to challenge participants. Participants will be instructed to exercise with a targeted intensity of 70-85% of the age-predicted maximum heart rate. Upon completion of each session, the harness will be doffed with skin checks to ensure no adverse effects have occurred. Heart rate, blood pressure, and oxygen saturation will be recorded. Participants will complete 3 training sessions per week for 12 weeks.

Trial Locations (1)

60611

Shirley Ryan AbilityLab, Chicago

All Listed Sponsors
collaborator

University of Alberta

OTHER

lead

Shirley Ryan AbilityLab

OTHER

NCT06873776 - Arm and Leg Cycling for Accelerated SCI Recovery | Biotech Hunter | Biotech Hunter