62
Participants
Start Date
January 15, 2025
Primary Completion Date
July 15, 2025
Study Completion Date
July 15, 2025
N-Acetylcysteine (NAC) Treatment
Participants in this group received N-Acetylcysteine (NAC) at a dose of 140 mg/kg orally or via a nasogastric tube every 4 hours for the first 16 hours, followed by the same dose at intervals of 6-8 hours for a total of 3 days, alongside standard supportive care for acute liver failure.
Standard supportive care
Participants in this group received only standard supportive care for acute liver failure, without N-Acetylcysteine (NAC). Standard supportive care included measures to prevent hypoglycemia, administration of broad-spectrum antimicrobials, proton pump inhibitors, fluid and electrolyte balance maintenance, and supportive treatment for hepatic encephalopathy.
Lahore General Hospital, Lahore, Lahore
Lahore General Hospital
OTHER_GOV