DIscontinuation of Anticoagulation Guided by Smartwatch in Post-ablation Patients With Atrial Fibrillation

NARecruitingINTERVENTIONAL
Enrollment

5,694

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2029

Conditions
Atrial Fibrillation (AF)
Interventions
DEVICE

PPG/ECG dual mode based smartwatch

The intervention initiates anticoagulation when AF is detected as either a single episode ≥1 hour or cumulative ≥2 hours/24h (adjusted for monitoring compliance), triggering a 30-day NOAC therapy cycle that restarts if AF recurs during treatment. Participants are required to wear the device ≥12 hours daily, supported by automated reminders (vibration/SMS/phone alerts) and a reward system to reinforce adherence.

DRUG

Continuous DOAC therapy

Continuous standard-dose DOAC therapy with dose adjustments per the drug labels.

Trial Locations (16)

100029

RECRUITING

Beijing Anzhen Hospital, Beijing

110004

NOT_YET_RECRUITING

Shengjing Hospital Affiliated to China Medical University, Shenyang

116023

NOT_YET_RECRUITING

First Affiliated Hospital of Dalian Medical University, Dalian

130021

NOT_YET_RECRUITING

The First Hospital of Jilin University, Changchun

150001

NOT_YET_RECRUITING

The First Affiliated Hospital of Harbin Medical University, Harbin

210036

NOT_YET_RECRUITING

The First Affiliated Hospital of Nanjing Medical University, Nanjing

221002

NOT_YET_RECRUITING

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

230022

NOT_YET_RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

250012

NOT_YET_RECRUITING

Qilu Hospital of Shandong University, Jinan

252000

NOT_YET_RECRUITING

Liaocheng People's Hospital, Liaocheng

310009

NOT_YET_RECRUITING

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou

430030

NOT_YET_RECRUITING

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

450003

NOT_YET_RECRUITING

Henan Provincial Chest Hospital, Zhengzhou

462003

NOT_YET_RECRUITING

Luohe Central Hospital, Luohe

611130

NOT_YET_RECRUITING

Chengdu Fifth People's Hospital, Chengdu

050000

NOT_YET_RECRUITING

The Second Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

Beijing Anzhen Hospital

OTHER

NCT06871228 - DIscontinuation of Anticoagulation Guided by Smartwatch in Post-ablation Patients With Atrial Fibrillation | Biotech Hunter | Biotech Hunter