Role of Non-Selective Beta-Adrenergic Blocker in Severe TBI

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 20, 2025

Primary Completion Date

September 20, 2025

Study Completion Date

September 20, 2025

Conditions
Traumatic Brain Injury (TBI) PatientsIntracranial PressureIntensive Care UnitMortality
Interventions
DRUG

propranolol

This group Will receive propranolol intravenously at a dose of 1 mg every 6 h for 7 days, and doses will be held if heart rate less than 60 bpm, mean arterial pressure less than 65 mmHg

DRUG

normal saline IV

This group Will receive 1ml of sterile 0.9% normal saline IV every 6 hours for 7 days

Trial Locations (1)

31527

Tanta University, Tanta

All Listed Sponsors
lead

Tanta University

OTHER