30
Participants
Start Date
March 6, 2025
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2027
No Salt, No β-OHB
Participants will consume the following for ten days. Enteric capsules will be filled with a dextrose placebo. The placebo supplement will be a β-OHB-free, taste and viscosity-matched, beverage produced by KetoneAid.
High Salt, No β-OHB
Participants will consume the following for ten days. Enteric capsules will be filled with Morton's table salt. Sodium consumption will be normalized to caloric intake (2 mg Sodium/Calorie). The placebo supplement will be a β-OHB-free, taste and viscosity-matched, beverage produced by KetoneAid.
High Salt, High β-OHB
Participants will consume the following for ten days. Enteric capsules will be filled with Morton's table salt. Sodium consumption will be normalized to caloric intake (2 mg Sodium/Calorie). Ketone beverage will be the β-OHB supplement produced by KetoneAid. Participants will consume 24 mL (12 grams β-OHB) of the ketone beverage three times a day (total 36 grams β-OHB).
RECRUITING
School of Public Health, Bloomington
University of Utah
OTHER
University of Missouri-Columbia
OTHER
National Institute on Aging (NIA)
NIH
Indiana University
OTHER