Phase II Clinical Study of Befotertinib in EGFR Non-classical Mutant NSCLC

PHASE2RecruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

December 30, 2027

Conditions
NSCLC (Non-small Cell Lung Cancer)
Interventions
DRUG

befotertinib

Befotertinib will be administered orally at an initial dose of 75 mg once daily for 21 days, with escalation to 100 mg if tolerated. Treatment continues until disease progression, unacceptable toxicity, or withdrawal.

Trial Locations (1)

310000

RECRUITING

2nd Affiliated Hospital, School of Medicine, Hangzhou

All Listed Sponsors
collaborator

The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital

UNKNOWN

collaborator

Hunan Cancer Hospital - the Affiliated Cancer Hospital of Xiangya school of Medicine, Central South University

UNKNOWN

collaborator

Taizhou Hospital

OTHER

collaborator

West China Hospital

OTHER

lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER