PEG-rhGH and Semaglutide Combination Therapy in Non-Diabetic Obese Adults

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

Not specified

Conditions
Non-diabetic Obesity
Interventions
DRUG

PEG-rhGH Injection + Semaglutide Injection

"Polyethylene Glycol Recombinant Human Growth Hormone Injection (PEG-rhGH Injection), 54 IU/9.0 mg/1.0 mL/amp.; Subcutaneous injection using pen-injector, once weekly at a dose of 2 mg per week (weeks 1-40).~Semaglutide Injection, 0.68 mg/mL,1.5 mL;1.34 mg/mL,1.5 mL;1.34 mg/mL,3 mL;2.27 mg/mL,3 mL;3.2 mg/mL,3 mL; Subcutaneous injection once weekly using pre-filled pen including dosage escalation period (W1-W16): starting dose 0.25 mg, increasing every 4 weeks (0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, 2.4 mg) and maintenance treatment period (W17-W40): at a dose of 2.4 mg for 24 weeks"

DRUG

Semaglutide Injection

Semaglutide Injection, 0.68 mg/mL,1.5 mL;1.34 mg/mL,1.5 mL;1.34 mg/mL,3 mL;2.27 mg/mL,3 mL;3.2 mg/mL,3 mL; Subcutaneous injection once weekly using pre-filled pen including dosage escalation period (W1-W16): starting dose 0.25 mg, increasing every 4 weeks (0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, 2.4 mg) and maintenance treatment period (W17-W40): at a dose of 2.4 mg for 24 weeks

Trial Locations (1)

200032

Zhongshan Hospital Affiliated to Fudan University, Shanghai

All Listed Sponsors
lead

Shanghai Zhongshan Hospital

OTHER